Top results (loci containing at least one meta-analysis result with P < 0.0001)

Polymorphism Location (hg19) Gene Ethnicity # Samples # Studies Allele contrast 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs3849942 chr9:27543280 C9orf72 [-3264bp] All: C 20,662 14 T vs. C 0.217 (T) 0.058 (T) 1.20 (1.14-1.26) 73 (54-84) 3.61e-12
rs2708909 chr7:48051679 SUN3 All: C 8,137 4 G vs. T 0.392 (G) 0.275 (T) 1.19 (1.11-1.27) 0 (0-77) 8.53e-07
rs11082762 chr18:21365852 LAMA3 All: C 7,520 8 A vs. G 0.467 (A) 0.125 (G) 1.17 (1.09-1.25) 0 (0-42) 6.15e-06
rs2303565 chr2:219545308 STK36 All: C 7,520 8 C vs. T 0.333 (C) 0.15 (C) 1.16 (1.09-1.24) 30 (0-69) 7.49e-06
rs9533799 chr13:44808173 intergenic All: C 7,520 8 A vs. C 0.408 (A) 0.108 (A) 1.16 (1.09-1.24) 0 (0-55) 9.92e-06
rs16856202 chr1:232155150 DISC1 All: C 8,151 8 G vs. T 0.033 (G) 0.108 (G) 0.66 (0.55-0.80) 0 (0-58) 1.28e-05
rs10491104 chr17:15884560 ZSWIM7 All: C 7,520 8 T vs. C 0.408 (T) 0.133 (T) 0.87 (0.81-0.92) 0 (0-60) 1.32e-05
rs2405657 chr11:97682563 intergenic All: C 14,092 8 A vs. G 0.3 (A) 0.425 (G) 0.86 (0.80-0.92) 28 (0-68) 1.35e-05
rs1997368 chr9:102713579 STX17 All: C 7,520 8 G vs. A 0.317 (G) 0.183 (G) 1.17 (1.09-1.25) 0 (0-66) 1.70e-05
rs1776148 chr1:242042544 EXO1 All: C 14,948 8 A vs. G 0.275 (A) 0.217 (A) 1.16 (1.08-1.24) 0 (0-38) 2.69e-05
rs4980270 chr10:124951378 BUB3 [+26492bp] All: C 7,520 8 T vs. C 0.1 (T) 0.217 (T) 1.23 (1.12-1.36) 0 (0-5) 3.22e-05
rs7995844 chr13:39872236 LHFP [-44793bp] All: C 7,520 8 G vs. A 0.35 (G) 0.317 (G) 1.15 (1.08-1.23) 0 (0-43) 3.90e-05
rs11803905 chr1:107989313 NTNG1 All: C 7,520 8 T vs. C 0.317 (T) 0.2 (T) 0.86 (0.80-0.92) 0 (0-58) 4.35e-05
rs4266653 chr8:22169086 PIWIL2 All: C 7,520 8 G vs. A 0.475 (G) 0.175 (A) 1.14 (1.07-1.22) 0 (0-6) 4.84e-05
rs1735970 chr21:23124088 intergenic All: C 7,520 8 A vs. G 0.317 (A) 0.108 (A) 0.86 (0.80-0.93) 0 (0-67) 5.13e-05
rs3847437 chr10:11452259 USP6NL [-43686bp] All: C 7,520 8 T vs. C 0.042 (T) 0.092 (T) 0.73 (0.62-0.85) 0 (-) 5.74e-05
rs7436874 chr4:8650823 CPZ [+29335bp] All: C 7,520 8 C vs. T 0.358 (C) 0.35 (T) 0.87 (0.82-0.93) 0 (0-62) 6.76e-05
rs10510480 chr3:17867999 TBC1D5 All: C 7,520 8 C vs. T 0.108 (C) 0.45 (C) 1.25 (1.12-1.40) 0 (0-65) 7.33e-05
rs571890 chr18:10026086 intergenic All: C 7,000 8 T vs. C 0.475 (T) 0.342 (T) 0.88 (0.82-0.94) 0 (0-64) 7.92e-05
rs12462372 chr19:56373461 NLRP4 All: C 7,520 8 A vs. G 0.083 (A) 0.267 (A) 1.35 (1.16-1.56) 0 (0-66) 9.10e-05
rs1120599 chr1:209670781 intergenic All: A, C 12,366 10 T vs. C 0.292 (T) 0.242 (T) 1.12 (1.06-1.19) 42 (0-72) 9.46e-05
rs7767170 chr6:132208492 ENPP1 All: C 7,520 8 T vs. C 0.017 (T) - 1.56 (1.25-1.96) 0 (-) 9.92e-05