rs2306677, chr12:26636386 (ITPR2)

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Forest plot for this polymorphism

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Polymorphism	Location (hg19)	Gene	Allele contrast	Ethnicity	# Studies	# Samples	1000G CEU	1000G CHB+JPT	Meta OR (95%CI)	I2 (95%CI)	Meta P-value
rs2306677	chr12:26636386	ITPR2	A vs. G	All: A, C	5	3,576	0.092 (A)	0.217 (A)	0.90 (0.78-1.03)	0 (0-51)	0.118
rs2306677	chr12:26636386	ITPR2	A vs. G	C	3	2,636	0.092 (A)	0.217 (A)	0.94 (0.79-1.12)	0 (0-65)	0.473

Association studies for this polymorphism [-][+]

Study	PubMed	Title [+]	Ethnicity	Population	# Cases	# Controls
Chen, 2012	22795786	No association of five candidate genetic variants with amyotrophic lateral sclerosis in a Chinese population. [-]No association of five candidate gen... [+]	A	China	395	288
Deng, 2013	23624525	Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. [-]Genome-wide association analyses in ... [+]	A	China (REP)	706	1,777
Fernández-Santiago, 2011	19464757	No evidence of association of FLJ10986 and ITPR2 with ALS in a large German cohort. [-]No evidence of association of FLJ109... [+]	C	Germany	595	681
Iida, 2011	21665992	A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese. [-]A functional variant in ZNF512B is a... [+]	A	Japan (discovery stage 1)	92	233
Kwee, 2012	22470424	A high-density genome-wide association screen of sporadic ALS in US veterans. [-]A high-density genome-wide associati... [+]	C	USA, UK (GWAS+REP)	625	7,219
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	Belgium (GWAS)	305	341
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	France (REP)	230	709
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	Germany (REP)	1,030	1,715
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	Ireland (GWAS)	221	211
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	Ireland (REP)	103	128
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	Netherlands (GWAS)	1,046	7,704
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	Netherlands (REP)	108	1,935
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	Poland (REP)	183	544
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	Sweden (GWAS)	476	486
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	UK (REP)	212	237
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	USA (GWAS)	275	271
van Es, 2009	19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. [-]Genome-wide association study identi... [+]	C	USA (REP)	666	672
van Es, 2007	17827064	ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. [-]ITPR2 as a susceptibility gene in sp... [+]	C	Belgium (REP1)	291	267
van Es, 2007	17827064	ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. [-]ITPR2 as a susceptibility gene in sp... [+]	C	Netherlands (GWAS)	461	450
van Es, 2007	17827064	ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. [-]ITPR2 as a susceptibility gene in sp... [+]	C	Netherlands (REP1)	272	336
van Es, 2007	17827064	ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. [-]ITPR2 as a susceptibility gene in sp... [+]	C	Sweden (REP2)	313	303